Artist Conk Mushroom vs. Diabetic Complications
The white underside of the mushroom Artist Conk (Ganoderma applanatum) turns brown when bruised and can be intricately etched into detailed carvings, hence the English common name of this ubiquitous American tree fungus.
Artist Conks can live for 50 years and grow to arms width or more. David Arora of the mushroom identification guide Mushrooms Demystified says that along with the Red-belted Conk (Fomitopsis pinicola), Artist Conk is "the most common conk in our area [USA]." [400]
Artist Conk can be found growing on practically every species of hardwood tree, plus many conifers, including Douglas Fir. Arora says, "The only regions where it seems to be absent are those where there aren't any trees!" [400]
Our ancestors would burn Artist Conk because it produced not only a pleasant odor but an insect repelling smoke as well. [25]
In 2008, a study by Jeong et al. stated that an isolated compound from Artist Conk "significantly inhibited the growth of solid tumor [Sarcoma-180] and increased the natural killer (NK) cell activity." [401] NK cells, or Natural Killer cells, are white blood cells that form a vital part in the human immune system's cancer fighting arsenal. At least four additional studies have also reported positive findings in regards to the anti-tumor properties of Ganoderma applanatum. [402, 403, 404, 405]
Another area of interest in the study of Artist Conk extract has been its effect on blood sugar and potential to inhibit some of the complications of diabetes. A study in 2007 found that a compound extracted from Artist Conk was able to lower the glucose levels in body fluids by 22.0%, and cholesterol and triglyceride levels by 20.3%. [406] The glucose lowering effect of an alcohol extract of Artist Conk was previously noted in a study by Jung in 2005. [407]
Perhaps of even greater interest than the blood glucose lowering effect of Artist Conk is its potential to help inhibit diabetic complications, which was the main focus of the 2005 study by Jung et al. It is commonly believed in the scientific community that the enzyme aldose reductase is largely responsible for the organ complications seen in diabetes. No less than three studies on Artist Conk extract have reported that it powerfully inhibits aldose reductase activity, thus suggesting a potential protective effect against diabetic complications. [407, 408, 409] "These results suggested that G. applanatum [Artist Conk] might possess constituents with anti-diabetic and inhibitory effects on diabetic complications," concludes Jung.
Looking at other research on Artist Conk, a 2005 study reported a polysaccharide extract of Artist Conk as strengthening the gastric mucosa barrier, useful in cases gastric ulcers. [410] Other papers have reported Artist Conk extracts as anti-viral, [414] anti-bacterial, [411, 412, 413] anti-parasitic and diuretic, [415] antioxidant, [416] and immune boosting. [25]
In addition, Paul Stamets also lists respiratory conditions and inflammation as areas where research has shown Artist Conk extract to be beneficial, in his book Mycelium Running. [134]
Note: The statements on this page have not been evaluated by the Food and Drug Administration. This article is not intended to diagnose, treat, cure or prevent any disease. Never use any medicinal mushroom or herb without prior approval by a medical doctor. - 17268
Artist Conks can live for 50 years and grow to arms width or more. David Arora of the mushroom identification guide Mushrooms Demystified says that along with the Red-belted Conk (Fomitopsis pinicola), Artist Conk is "the most common conk in our area [USA]." [400]
Artist Conk can be found growing on practically every species of hardwood tree, plus many conifers, including Douglas Fir. Arora says, "The only regions where it seems to be absent are those where there aren't any trees!" [400]
Our ancestors would burn Artist Conk because it produced not only a pleasant odor but an insect repelling smoke as well. [25]
In 2008, a study by Jeong et al. stated that an isolated compound from Artist Conk "significantly inhibited the growth of solid tumor [Sarcoma-180] and increased the natural killer (NK) cell activity." [401] NK cells, or Natural Killer cells, are white blood cells that form a vital part in the human immune system's cancer fighting arsenal. At least four additional studies have also reported positive findings in regards to the anti-tumor properties of Ganoderma applanatum. [402, 403, 404, 405]
Another area of interest in the study of Artist Conk extract has been its effect on blood sugar and potential to inhibit some of the complications of diabetes. A study in 2007 found that a compound extracted from Artist Conk was able to lower the glucose levels in body fluids by 22.0%, and cholesterol and triglyceride levels by 20.3%. [406] The glucose lowering effect of an alcohol extract of Artist Conk was previously noted in a study by Jung in 2005. [407]
Perhaps of even greater interest than the blood glucose lowering effect of Artist Conk is its potential to help inhibit diabetic complications, which was the main focus of the 2005 study by Jung et al. It is commonly believed in the scientific community that the enzyme aldose reductase is largely responsible for the organ complications seen in diabetes. No less than three studies on Artist Conk extract have reported that it powerfully inhibits aldose reductase activity, thus suggesting a potential protective effect against diabetic complications. [407, 408, 409] "These results suggested that G. applanatum [Artist Conk] might possess constituents with anti-diabetic and inhibitory effects on diabetic complications," concludes Jung.
Looking at other research on Artist Conk, a 2005 study reported a polysaccharide extract of Artist Conk as strengthening the gastric mucosa barrier, useful in cases gastric ulcers. [410] Other papers have reported Artist Conk extracts as anti-viral, [414] anti-bacterial, [411, 412, 413] anti-parasitic and diuretic, [415] antioxidant, [416] and immune boosting. [25]
In addition, Paul Stamets also lists respiratory conditions and inflammation as areas where research has shown Artist Conk extract to be beneficial, in his book Mycelium Running. [134]
Note: The statements on this page have not been evaluated by the Food and Drug Administration. This article is not intended to diagnose, treat, cure or prevent any disease. Never use any medicinal mushroom or herb without prior approval by a medical doctor. - 17268
About the Author:
Dr. Rafael has worked with natural health since finishing Chiropractic College in 1996. He currently specializes in medicinal mushrooms, working with the extracts of Paul Stamets, including the synergistic MycoSoft Gold Formula including Artist Conk. For research references to this article, please go to the Ganoderma applanatum medicinal research page.
posted by X - Men at
11:23 AM
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